Patents

1  Leontis NB, and Afonin KA. RNA complexes featuring paranemic binding, methods of their production and sensors and analytical methods involving same. US Patent No. 8129516 

2   Shapiro BA, Yingling Y, Bindewald E, Kasprzak W, Jaeger L, Severcan I, Geary C, Afonin KA. RNA Nanoparticles and Methods of Use. US Patent No. 2010148085

3    Shapiro BA, Yingling Y, Bindewald E, Kasprzak W, Jaeger L, Severcan I, Geary C, Afonin KA. RNA Nanoparticles and Nanotubes. US Patent No. 20120263648

4   Shapiro BA, Afonin KA, Viard M, Bindewald E. Auto-recognizing therapeutic R/DNA chimeric nanoparticles (NP). WO Patent 2013075140

5   Shapiro BA, Bindewald E, Afonin KA, Santhanam AN, Jaeger L. Therapeutic RNA switches compositions and methods of use. WO Patent 2013075132

6    Shapiro BA, Afonin KA, Kireeva M, Kashlev M, Jaeger L, and Grabow WW. Co-transcriptional assembly of modified RNA nanoparticles. U.S. Patient Application No. 61/698,277 filed September 7, 2012 (pending)

7    Shapiro BA, Afonin KA, Viard M, Martins AN. Multifunctional RNA nanoparticles and methods of use. U.S. Patient Application No. 61/878,758 filed September 17, 2013 (pending)

8    Jones M, Afonin KA. Programmable formation of quantum dot lattices for biosensing with fluorescent blinking. U.S. Patent Application No. 62/353,155 filed June 22, 2016 (pending)

9    Shapiro BA, Afonin KA, Viard M. Triggering RNA interference with RNA-DNA and DNA-RNA nanoparticles. WO Patent 2015/171827

10    Shapiro BA, Afonin KA, Bindewald E, Viard M, Kasprzak W, Dobrovolskaia M, Halman JR. Functionally-interdependent shape switching nucleic acid anticubes and other nanoparticles. U.S. Patient Application No. 62/480,899 filed April 3, 2017 (pending)

1   NCI (Technology Transfer Center) executed a start-up-exclusive evaluation license with Sixfold Bioscience, Inc. for E-078-2016/0-      EIR-00, “Triggering of multiple functionalities using minimal RNA toeholds in RNA-based nanoparticles”. This license was negotiated by Jasmine Yang.

2   NCI (Technology Transfer Center) executed a start-up-exclusive evaluation license with Sixfold Bioscience, Inc. for E-765-2013/0-      EIR-00, “Multifunctional RNA Nanoparticles”. This license was negotiated by Jasmine Yang.

Licensed Patents