1   Shapiro BA, Yingling Y, Bindewald E, Kasprzak W, Jaeger L, Severcan I, Geary C, Afonin KA. RNA nanoparticles and methods of use. US Patent No. US2010148085

2   Leontis NB, and Afonin KA. RNA complexes featuring paranemic binding, methods of their production and sensors and analytical methods involving same. US Patent No. US8129516B1

3   Shapiro BA, Afonin KA, Viard M, Bindewald E. Auto-recognizing therapeutic R/DNA chimeric nanoparticles (NP). U.S. Patent No. US9631192

4   Shapiro BA, Bindewald E, Afonin KA, Santhanam AN, Jaeger L. Therapeutic RNA switches compositions and methods of use. WO Patent No. WO2013075132A1

5   Shapiro BA, Afonin KA, Viard M. Triggering RNA interference with RNA-DNA and DNA-RNA nanoparticles. US Patent No. US20170274000A1

6   Shapiro BA, Yingling Y, Bindewald E, Kasprzak W, Jaeger L, Severcan I, Geary C, Afonin KA. RNA Nanoparticles and Nanotubes. US Patent No. US9732337B2

7   Shapiro BA, Afonin KA, Kireeva M, Kashlev M, Jaeger L, and Grabow WW. Co-transcriptional assembly of modified RNA nanoparticles. U.S. Patent No. US9719084B2

8   Shapiro BA, Afonin KA, Viard M, Martins AN. Multifunctional RNA nanoparticles and methods of use. U.S. Patent No. US10301621

9  Jones M, Afonin KA. Methods and compositions for biosensing. U.S. Patent No. US10627404B2

10  Aksimentiev A, Afonin KA, Wanunu M. Nucleic acid nanoparticles for analyte detection. US Patent No. 10,900,067.

11  Shapiro BA, Afonin KA, Bindewald E, Viard M, Kasprzak W, Dobrovolskaia M, Halman JR. Functionally-interdependent shape switching nucleic acid anticubes and other nanoparticles. U.S. Patent Application No. 62/480,899 filed April 3, 2017

12  Dobrovolskaia MA, Afonin KA, Hong E, Halman JR. Nucleic acid nanoparticles (NANPs) and methods of using the same for controlled immunomodulation, filed 2018

13  Afonin KA, Tabdanov E, Zhovmer A. Programmable Mechanobiological Platform. U.S. Patent Application No. 62/549,032 filed April 24, 2020

1   NCI (Technology Transfer Center) executed a start-up-exclusive evaluation license with Sixfold Bioscience, Inc. for E-078-2016/0-      EIR-00, “Triggering of multiple functionalities using minimal RNA toeholds in RNA-based nanoparticles”. This license was negotiated by Jasmine Yang.

2   NCI (Technology Transfer Center) executed a start-up-exclusive evaluation license with Sixfold Bioscience, Inc. for E-765-2013/0-      EIR-00, “Multifunctional RNA Nanoparticles”. This license was negotiated by Jasmine Yang.

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